Colon targeted beads loaded with pterostilbene: Formulation, optimization, characterization and in vivo evaluation
Background: Pterostilbene has a proven chemopreventive effect for colon carcinogenesis but suffers low bioavailability limitations and therefore unable to reach the colonic tissue.Objective and methodology: To overcome the issue of low bioavailability, pterostilbene was formulated into an oral colon targeted beads by ionic gelation method using pec